pentobarbital will lower the level or impact of mestranol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
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fentanyl intranasal and pentobarbital both maximize sedation. Stay clear of or Use Alternate Drug. Restrict use to individuals for whom alternative cure alternatives are inadequate
pentobarbital will decrease the level or impact of ambrisentan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.
pentobarbital will lessen the level or outcome of nisoldipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will reduce the level or impact of fesoterodine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will decrease the level or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
Contraindicated (1)pentobarbital will lessen the level or effect of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with robust more info CYP3A4 inducers can result in lessened serum concentrations and loss of antimalarial efficacy
pentobarbital will lessen the level or outcome of eltrombopag by impacting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Keep track of.
pentobarbital will minimize the extent or result of diltiazem by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will lower the level or outcome of darunavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
Contraindicated (1)pentobarbital will reduce the level or effect of lorlatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Monitor Closely (one)pentobarbital will lessen the extent or impact of fentanyl transmucosal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Coadministration of fentanyl with CYP3A4 inducers could lead on to the decrease in fentanyl plasma concentrations, deficiency of efficacy or, possibly, progress of a withdrawal syndrome in a individual who's got made physical dependence to fentanyl. Immediately after stopping a CYP3A4 inducer, given that the effects of the inducer decline, the fentanyl plasma concentration will boost which could enhance or extend both the therapeutic and adverse effects.